Customer question: I’ve been supplementing with TF Plus and feel like my blood pressure might be going up, and I sense some unease around my heart. Is this normal?
Legal disclaimer
We’re answering as a supplement distributor, not a medical professional. 4Life Transfer Factor Plus Tri-Factor Formula is a food supplement, not a medication. It is not intended to diagnose, treat, or prevent any disease. Always consult a doctor when in doubt.
Among thousands of customers who use Transfer Factor Plus, we’ve received just one message describing unusual sensations related to heart rhythm or blood pressure. Most people report feeling well and supplement without issues.

TF Plus contains a variety of ingredients, including zinc, medicinal mushrooms, and botanical extracts. While all ingredients are considered safe for general use, individual reactions may occur due to personal sensitivities, allergies, or interactions with other supplements, medications, or even food.
Zinc contributes to the proper function of the immune system (EFSA Journal 2009;7(9):1229), and also plays a role in regulating blood pressure and heart rhythm. For most people, it’s a beneficial mineral — but in rare cases, unexpected effects may be linked to individual differences, stress, or nervous system reactivity.
In any situation involving discomfort, we recommend pausing supplementation and consulting a qualified healthcare provider. Each body is different, and personalized advice is always best.
Looking for cardiovascular support?
4Life also offers a supplement aimed at supporting cardiovascular health: Transfer Factor BCV. While not a medication, it can help you enrich your daily diet with targeted nutrients for heart and vessel health.

Author: Alicja Krzywańska-Podermańska
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